Overview of Picked Chemical Compounds and Intermediates
Overview of Picked Chemical Compounds and Intermediates
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1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is certainly an impurity related to bortezomib, a proteasome inhibitor used in the remedy of a number of myeloma. Its synthesis or examine is very important for making sure the purity and protection with the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor within the synthesis of abiraterone acetate, a drug used in the therapy of prostate cancer by inhibiting androgen manufacturing.
Imatinib Intermediate (CAS NO. 152460-10-1): A key compound from the synthesis of imatinib, a drug that targets distinct varieties of cancer, like Continual myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Employed in the synthesis of docetaxel, a chemotherapy medication that treats a variety of cancers such as breast, lung, and prostate cancer.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): They're intermediates during the synthesis of gemcitabine, an anti-cancer drug. Their analyze is significant for optimizing the manufacturing course of action and ensuring substantial purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-5): Lapatinib is applied to treat breast most cancers, and these intermediates are linked to its manufacturing.
Fulvestrant Intermediates: Fulvestrant can be an estrogen receptor antagonist Utilized in the treatment of breast cancer. A variety of intermediates assist in the synthesis of the drug.
Paclitaxel Side Chain Acid (CAS NO. 949023-sixteen-nine): This intermediate is used in the synthesis of paclitaxel, a chemotherapy drug CAS NO. 122111-01-7 helpful in treating cancers for instance ovarian, breast, and lung most cancers.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug Employed in the remedy of colorectal cancer and smaller mobile lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-82-9): This compound is involved with the synthesis of adamantane derivatives, that have various applications, like antiviral Houses.
Vildagliptin Intermediates: Employed in the creation of vildagliptin, an oral drug for type 2 diabetes that inhibits the enzyme DPP-4 to regulate blood sugar stages.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-one): This compound is involved in the synthesis of assorted gluconic acid derivatives, that FULVESTRANT INTERMEDIATES--4(N-4) are Utilized in foods, pharmaceutical, and industrial apps.
Canagliflozin Intermediate two: A precursor from the synthesis of canagliflozin, a medication employed to handle sort 2 diabetic issues by inhibiting sodium-glucose co-transporter two (SGLT2).